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The ongoing responsibilities of caring for the collection includes the research and continual reassessment of the museum's holdings in order to continually refine and improve the quality, focus and appropriateness of the collection to best serve the museum's mission.

Judicious deaccessioning - the removal and disposal of works from the collection by sale or transferred as a gift to another more appropriate public institution - is a key step in collection care and development. Any funds received from the disposal of works are used for purchasing other works of art for the museum's collection.

The Nasher Museum agrees with and supports the current deaccessioning guidelines developed by the Association of American Museum Directors as part of "Professional Practices in Art Museums." In keeping with those guidelines, the Nasher Museum makes current deaccession information available to the public through this site. Due to the ongoing nature of this process, the works included here do not represent the entirety of those deaccessioned by the Nasher Museum or the former Duke University Museum of Art.